Spectral Focusing Timing and Recombination Unit, Dual Output Laser Sources

Developed by scientists in Newport’s Technology and Applications Center (TAC), the SF-TRU is engineered to synchronize the two output beams of dual-output laser sources, facilitating a large variety of single- and dual-beam, multiphoton imaging and ultrafast spectroscopy applications, such as:

• Single- and multi-color (wavelength mixing) two-photon fluorescence (TPF)
• Second harmonic generation (SHG)
• Third harmonic generation (THG)
• Coherent anti-Stokes Raman scattering (CARS)
• Stimulated Raman scattering (SRS)
• Pump-probe
• Transient absorption
• Fluorescence resonance energy transfer (FRET)
• Two-photon uncaging

The SF-TRU module enables hyperspectral CARS/SRS imaging with spectral resolution up to 5 cm-1. High spectral resolution is achieved by employing spectral focusing with tunable-distance grating pairs, which, in contrast with fixed-length glass rods, allows matching the spectral resolution and the linewidths of the Raman lines of interest.